AI-Assisted Diagnostics

Paige’s AI-assisted diagnostic and biomarker AI applications meet the highest standards and are designed to support some of the most challenging cases cancer.

AI-Assisted Diagnostic Applications

Paige Prostate Suite

The Paige Prostate Suite is a group of comprehensive AI-powered applications that aid in the detection and grading of prostate cancer on H&E-stained whole-slide images of prostate needle biopsies.

  • Paige Prostate Detectii  - Assists in the detection of foci suspicious for cancer

  • Paige Prostate Grade & Quantify*  - Categorizes areas suspicious for cancer by Gleason pattern, providing a primary and secondary Gleason grade prediction, as well as a percentage and linear measurement of tumor burden

  • Paige Prostate Perineural Invasion (PNI)*  - Aids in the detection of suspicious foci around nerve fiber, identifying the presence of PNI

Paige GI Suite†

The Paige GI Suite is a new and powerful portfolio of AI-powered applications designed to support pathologists in the detection and classification of benign and malignant condition across the entire gastrointestinal tract.  Built off Paige’s latest foundation model technology this represents the most powerful range of diagnostic AI applications for GI pathology.

  • Paige GI Detect & Subtype†  : Detect, classify and localize cancer, pre-cancer and benign lesions in biopsies and resection specimens from anywhere across the GI systems including esophagus, stomach, small intestine, gall bladder, pancreas, large bowel and rectum.

  • Paige Colon Detect*  - Identifies foci suspicious for colon carcinoma and high-grade dysplasia (HGD)

  • Paige Colon MSI± - Detects the presence or absence of high microsatellite instability (MSI-H) or mismatch repair-deficient (dMMR) phenotypes from colon biopsies and resections containing cancer

Paige Breast Suite

The Paige Breast Suite is a set of AI-powered applications designed to support pathologists in the identification and classification of breast cancer on H&E-stained whole-slide images from breast biopsy and excision specimens. By pinpointing suspicious tissue and accelerating the most challenging and tedious aspects of case analysis, the Paige Breast Suite helps pathologists make more efficient and consistent clinical decisions. 

  • Paige Breast Detect & Neoplasm*  - Highlights foci suspicious for cancer and pre-cancerous neoplasms

  • Paige Breast Mitosis*  - Identifies individual mitotic figures, locates the mitotic hotspot, and automatically calculates mitotic counts mitotic density

  • Paige Breast Lymph Node*  - Detects foci that are suspicious for breast cancer metastasis from lymph node specimens

  • Her2Complete ii – an AI assay that can measure Her2 expression from H&E samples, including the identification of HER-2 low patients

  • Studies have shown that Paige Breast Lymph Node AI can detect metastases of any size with 98% sensitivity and shorten the reading time of lymph node slides by as much as 55%5. 

Paige Pan-Cancer Detect±

A novel, first of its kind application that can detect regions of interest suspicious for cancer across 40 multiple organs and different tissues, including GI, GU, lung, cervix, endometrium, breast, skin, brain and rare cancer variants.

  • Evidence shows that this pan cancer systems can achieve 0.95 specimen level AUC across nine common and seven rare cancers6.

  • In digital workflows, can be used to prioritize cases for accelerated workflow

How pathologists are using Paige’s AI-assisted diagnostic applications

Every day, pathologists leverage Paige's AI applications to enhance their diagnostic confidence, improve workflow efficiencies, and ultimately deliver better patient care. From image analysis and decision support to workflow automation, Paige is being used to support hospitals and labs worldwide.

Prioritize cases or individual slides by identifying those suspicious for cancer

Quickly identify an area on the slide most suspicious for cancer, including hard-to-find or small malignant foci.

Automate laborious diagnostic tasks including measurement, quantification, and classification

Provide quality assurance

Seamless Integration Across Digital Pathology Platforms

Leveraging Paige’s AI open strategy, we enable seamless deployment across multiple scanners, image formats and digital pathology platforms. So whether you are using an established platform or exploring new digital IMS options, Paige will work with you to ensure a seamless AI experience and fit effortlessly into your lab workflows.

Redefining What Digital Pathology Can Do

Paige’s AI applications are designed to assist pathologists through routine workflows, offering customized solutions to meet the specific needs of each individual user. Powered by the Paige Platform, the only digital pathology solution built for AI, Paige and third-party applications are accessible at every step in the diagnostic process in easy-to-use visualizations, offering enhanced insights and efficiencies, streamlining clinical decision-making from the moment the image is generated until the final report is signed off. 

How Pathologists are using Paige’s Diagnostic AI

By harnessing the capabilities of Paige’s lab-tested AI applications, pathologists around the world are enhancing their diagnostic confidence, improving workflow efficiencies, and ultimately delivering better patient care. From image analysis and decision support to workflow automation, Paige is being used daily to:  

Prioritize cases or individual slides by identifying those suspicious for cancer 

Quickly identify an area on the slide most suspicious for cancer, including hard-to-find or small cancers 

Automate laborious diagnostic tasks including measurement, quantification, and classification 

Reduce false negative rates and provide quality assurance

Drive Efficiency Across the Entire Cancer Care Workflow

Drive Efficiency Across the Entire Cancer Care Workflow

Intuitive & Unique AI Visualizations 

Paige’s proprietary crosshair feature and TissueMap were thoughtfully designed to be easily utilized by pathologists during diagnosis. Carefully curated alongside the industry’s top pathologists, the AI visualizations highlight suspicious areas, rather than covering them with colored heatmaps that make detection difficult.

Trusted Technology Built for Clinical Use

With access to the largest dataset used for AI software development in pathology encompassing millions of slides from over 1,000 global institutions, Paige designs systems that empower laboratories with unparalleled knowledge. Our utilization of cutting-edge training techniques, including multiple instance learning, enables Paige products to work out of the box and generalize across any lab setting without requiring additional tuning. Our solutions exhibit remarkable robustness to pre-analytical variations and staining techniques, ensuring consistent and reliable performance on slides prepared at any lab and across any patient data without the need for on-site calibration. 

QUALITY AND SAFETY ARE TOP PRIORITY

CE-IVDD

& IVDR MARKS

UKCA

MARKS

FDA

Authorizations

ISO

13485:2016 Certification

MDSAP

Certification

"The authorization of this AI-based software can help increase the number of identified prostate biopsy samples with cancerous tissue, which can ultimately save lives."

— Office of In Vitro Diagnostics and Radiological Health, FDA Center for Devices and Radiological Health